Article
[Long QT syndrome: from clinical discovery to molecular etiopathogenesis].
Revue medicale de Liege - 1 Apr 1998
Czajkowski V, Kulbertus H
Abstract excerpt
Before the era of Molecular Biology the etiopathogenic mechanism of the long QT Syndrome (LQTS) was hypothetized to be an inhomogeneity in the innervation of the myocardium by the sympathetic system resulting in abnormal myocardial repolarisation, prolongation of the QT interval and various rhyth...
Topics
- Animals
- Autonomic Nervous System
- Calcium Channels
- Electrocardiography
- Heart Conduction System
- Humans
- Ion Channels
- Long QT Syndrome
- Molecular Biology
- Mutation
- Myocardium
- Potassium Channel Blockers
- Potassium Channels
- Proteins
- Sympathetic Nervous System
- Torsades de Pointes