Article

Temporal Variability of the Electromechanical Window in Long-QT Syndrome and Drug-Induced QT Prolongation: Value for Enhanced Arrhythmia-Risk Assessment

2025-09-05

Abstract excerpt

<h4>Structured Abstract</h4> <h4>Background</h4> Arrhythmia-risk assessment in congenital long-QT syndrome (LQTS) and drug-induced QT prolongation (diQTP) is primarily based on clinical, genetic, and electrical parameters. Electromechanical window (EMW; aortic-valve closure time minus QT interval) assessment outperformed QTc as a predictor of symptomatic status in LQTS. The relationship between QTc and EMW dynam...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 52af7048-6da6-5cc2-9635-18459468d55f
DOI: 10.1101/2025.09.03.25334690

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Temporal Variability of the Electromechanical Window in Long-QT Syndrome and Drug-Induced QT Prolongation: Value for Enhanced Arrhythmia-Risk AssessmentDOI 10.1101/2025.09.03.25334690Read

Electromechanical window negativity in genotyped long-QT syndrome patients: relation to arrhythmia risk.Semantic proximity Read

Beyond the length and look of repolarization: Defining the non-QTc electrocardiographic profiles of patients with congenital long QT syndrome.Semantic proximity Read

Decreased vector magnitudes may help identify events in patients with Long QT syndrome.Semantic proximity Read

Relation of increased short-term variability of QT interval to congenital long-QT syndrome.Semantic proximity Read

Assessment of ventricular repolarization variability with the DeltaT50 method improves identification of patients with congenital long QT syndromes.Semantic proximity Read

Architectural T-Wave Analysis and Identification of On-Therapy Breakthrough Arrhythmic Risk in Type 1 and Type 2 Long-QT Syndrome.Semantic proximity Read

Non-sustained microvolt level T-wave alternans in congenital long QT syndrome types 1 and 2.Semantic proximity Read

The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review.Semantic proximity Read

Catecholamine-provoked microvoltage T wave alternans in genotyped long QT syndrome.Semantic proximity Read

T-wave morphology after epinephrine bolus may reveal silent long QT syndrome mutation carriers.Semantic proximity Read

Prevalence and clinical phenotype of concomitant long QT syndrome and arrhythmogenic bileaflet mitral valve prolapse.Semantic proximity Read

Genotype-specific ECG patterns in long QT syndrome.Semantic proximity Read