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Article

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

Molecular biology reports - 1 Feb 2020

García-Tuñón Ignacio, Vuelta Elena, Lozano Laura, Herrero María, Méndez Lucía, Palomero-Hernandez Javier, Pérez-Caro María, Pérez-García Jessica, González-Sarmiento Rogelio, Sánchez-Martín Manuel

Abstract excerpt

The Nomo1 gene mediates a wide range of biological processes of importance in embryonic development. Accordingly, constitutive perturbation of Nomo1 function may result in myriad developmental defects that trigger embryonic lethality. To extend our understanding of Nomo1 function in postnatal stages and in a tissue-specific manner, we generated a conditional knockout mouse model of Nomo1. To achieve this, we used...

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PMID: 31833031
DOI: 10.1007/s11033-019-05214-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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