Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathological and molecular characterisation of 'multiple-classifier' endometrial carcinomas.

The Journal of pathology - 1 Mar 2020

León-Castillo Alicia, Gilvazquez Ester, Nout Remi, Smit Vincent Thbm, McAlpine Jessica N, McConechy Melissa, Kommoss Stefan, Brucker Sara Y, Carlson Joseph W, Epstein Elisabeth, Rau Tilman T, Soslow Robert A, Ganesan Raji, Matias-Guiu Xavier, Oliva Esther, Harrison Beth T, Church David N, Gilks C Blake, Bosse Tjalling

Abstract excerpt

Endometrial carcinoma (EC) molecular classification based on four molecular subclasses identified in The Cancer Genome Atlas (TCGA) has gained relevance in recent years due to its prognostic utility and potential to predict benefit from adjuvant treatment. While most ECs can be classified based on a single classifier (POLE exonuclease domain mutations - POLEmut, MMR deficiency - MMRd, p53 abnormal - p53abn), a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomarkers, Tumor

Share to Carcinoma, Endometrioid

Share to Endometrial Neoplasms

Share to Genetic factors in colorectal cancer

Share to Mutation

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 31829447
DOI: 10.1002/path.5373
PMCID: PMC7065184

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathological and molecular characterisation of 'multiple-classifier' endometrial carcinomas.PMID 31829447Read ↗

Clinicopathological characteristics of multiple-classifier endometrial cancers: a cohort study and systematic review.Semantic proximity Read ↗

Clinicopathological and molecular characterization of high-grade endometrial carcinoma with POLE mutation: a single center study.Semantic proximity Read ↗

Interpretation strategy of POLE, mismatch repair deficiency, and p53 in the multiple molecular classification of endometrial carcinoma and its clinical differences from single classification: a retrospective cohort study.Semantic proximity Read ↗

The emerging role of molecular pathology in directing the systemic treatment of endometrial cancerSemantic proximity Read ↗

Associations between molecular subtypes and high-risk pathological factors in endometrial cancer.Semantic proximity Read ↗

Endometrial Cancer Molecular Risk Stratification is Equally Prognostic for Endometrioid Ovarian Carcinoma.Semantic proximity Read ↗

Validation of a one-step genomics-based molecular classifier for endometrial carcinoma in a large Chinese population.Semantic proximity Read ↗

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.Semantic proximity Read ↗

TCGA Molecular Prognostic Groups of Endometrial Carcinoma: Current Knowledge and Future Perspectives.Semantic proximity Read ↗

Molecular Classification Outperforms Histologic Classification in Prognostication of High-grade Endometrial Carcinomas With Undifferentiated and Sarcomatous Components.Semantic proximity Read ↗

Distinct mutational landscape and clonal evolution of POLE-mutated endometrial cancer: geographic variation and insights into multiple classifier status.Semantic proximity Read ↗

Identification of TP53 mutated group using a molecular and immunohistochemical classification of endometrial carcinoma to improve prognostic evaluation for adjuvant treatments.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.