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The emerging role of molecular pathology in directing the systemic treatment of endometrial cancer

1 Jan 2021

Abstract excerpt

Following the discovery of the four molecular subtypes of endometrial cancer (EC) by The Cancer Genome Atlas (TCGA) in 2013, subsequent studies used surrogate markers to develop and validate a clinically relevant EC classification tool to recapitulate TCGA subtypes. Molecular classification combines focused sequencing ( POLE) and immunohistochemistry (mismatch repair and p53 proteins) to assign patients with EC...

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PMID: 34408794
DOI: 10.1177/17588359211035959

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