Identification of TP53 mutated group using a molecular and immunohistochemical classification of endometrial carcinoma to improve prognostic evaluation for adjuvant treatments.

doi:10.1136/ijgc-2019-000871

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Article

Identification of TP53 mutated group using a molecular and immunohistochemical classification of endometrial carcinoma to improve prognostic evaluation for adjuvant treatments.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2020

Beinse Guillaume, Rance Bastien, Just Pierre-Alexandre, Izac Brigitte, Letourneur Franck, Saidu Nathaniel Edward Bennett, Chouzenoux Sandrine, Nicco Carole, Goldwasser François, Batteux Frederic, Durdux Catherine, Chapron Charles, Pasmant Eric, Leroy Karen, Alexandre Jerome, Borghese Bruno

Abstract excerpt

INTRODUCTION: Molecular classification of endometrial carcinoma has been proposed to predict survival. However, its role in patient management remains to be determined. We aimed to identify whether a molecular and immunohistochemical classification of endometrial carcinoma could improve decision-making for adjuvant therapy. METHODS: All consecutive patients treated for endometrial carcinoma between 2010 and 2017...

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PMID: 32169874
DOI: 10.1136/ijgc-2019-000871

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