Clinicopathological characteristics of multiple-classifier endometrial cancers: a cohort study and systematic review.

doi:10.1136/ijgc-2023-004864

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Article

Clinicopathological characteristics of multiple-classifier endometrial cancers: a cohort study and systematic review.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 5 Feb 2024

De Vitis Luigi Antonio, Schivardi Gabriella, Caruso Giuseppe, Fumagalli Caterina, Vacirca Davide, Achilarre Maria Teresa, Aloisi Alessia, Garbi Annalisa, Zanagnolo Vanna, Aletti Giovanni, Guerini-Rocco Elena, Mariani Andrea, Maggioni Angelo, Barberis Massimo, Bogani Giorgio, Colombo Nicoletta, Multinu Francesco, Betella Ilaria

Abstract excerpt

BACKGROUND: Endometrial cancers with more than one molecular feature-POLE mutations (POLEmut), mismatch repair protein deficiency (MMRd), p53 abnormality (p53abn)-are called 'multiple classifiers'. OBJECTIVE: To describe our cohort of multiple classifiers and to report the results of a review on their incidence and the techniques used to identify them. METHODS: Multiple classifiers identified at the European...

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PMID: 38135437
DOI: 10.1136/ijgc-2023-004864

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Source receipt: pubmed, retrieved 7 Sept 2026.

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