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Article

Haplotypes of the plasminogen activator gene associated with ischemic stroke.

Thrombosis and haemostasis - 1 Sept 2006

Saito Kosuke, Nakayama Tomohiro, Sato Naoyuki, Morita Akihiko, Takahashi Teruyuki, Soma Masayoshi, Usami Ron

Abstract excerpt

Ischemic stroke (IS) is thought to be a multifactorial disorder associated with genetic backgrounds and environmental factors. In the circulating plasma, tissue plasminogen activator (tPA) catalyzes the reaction from plasminogen to plasmin. If there is a functional disability of tPA, induction of thrombosis and infarction disorders can occur. The aim of this study was to perform a haplotype-based case-control...

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Identifiers

PMID: 16953275
DOI: 10.1160/TH05-12-0830

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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