Article
The Relevance of SNPs at 3'UTR Region of CASP7 and miR-371b-5p Associated Diseases: A Computational Analysis.
Cell biochemistry and biophysics - 1 Dec 2020
Safdar Muhammad, Zaheer Sana, Khailany Rozhgar A, Parvez Sadaf, Naveed Muhammad, Bhuiyan Piplu, Ozaslan Mehmet, Moatasam Rebaz, Al-Attar Mustafa S, Khan Musarrat Abbas, Junejo Yasmeen
Abstract excerpt
The process of genetically programmed cell death, or apoptosis, plays a crucialrolein cellular homeostasis and gene expression. Disruption of apoptosis may lead to aberrant immune responses, cancer, and neurodegenerative diseases. Single nucleotide polymorphisms (SNPs) present in various microRNA (miRNA) genes and targets being an alteration of miRNA activity resulting in human diseases. Evidence reported that...
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