Article
Genetic variants in the promoters of let-7 are associated with the risk and age at onset of ischemic stroke: A case control study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Apr 2023
Wang Yuye, Qiu Luying, Jiang Wenjuan, Chen Meilin, He Zhiyi, Wang Yanzhe, Deng Shumin
Abstract excerpt
PURPOSE: Let-7 family members serve as crucial regulatory molecules in the pathogenesis of ischemic stroke. We predicted that genetic variations in the let-7 family's promoters may be linked to the risk of ischemic stroke. The connection of rs10877887 and rs13293512 in the let-7 family promoters with liability to ischemic stroke was explored in this study. PATIENTS AND METHODS: Clinical data and peripheral blood...
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