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Article

Comprehensive longitudinal study of epigenetic mutations in aging.

Clinical epigenetics - 9 Dec 2019

Wang Yunzhang, Karlsson Robert, Jylhävä Juulia, Hedman Åsa K, Almqvist Catarina, Karlsson Ida K, Pedersen Nancy L, Almgren Malin, Hägg Sara

Abstract excerpt

BACKGROUND: The role of DNA methylation in aging has been widely studied. However, epigenetic mutations, here defined as aberrant methylation levels compared to the distribution in a population, are less understood. Hence, we investigated longitudinal accumulation of epigenetic mutations, using 994 blood samples collected at up to five time points from 375 individuals in old ages. RESULTS: We verified earlier...

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Identifiers

PMID: 31818313
DOI: 10.1186/s13148-019-0788-9
PMCID: PMC6902582

Genes

CD19

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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