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Article

Age-related somatic mutations in the cancer genome.

Oncotarget - 22 Sept 2015

Milholland Brandon, Auton Adam, Suh Yousin, Vijg Jan

Abstract excerpt

Aging is associated with an increased risk of cancer, possibly in part because of an age-related increase in mutations in normal tissues. Due to their extremely low abundance, somatic mutations in normal tissues frequently escape detection. Tumors, as clonal expansions of single cells, can provide information about the somatic mutations present in these cells prior to tumorigenesis. Here, we used data from The...

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Identifiers

PMID: 26384365
DOI: 10.18632/oncotarget.5685
PMCID: PMC4694783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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