Article
Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease.
Biomolecules - 3 Dec 2019
Priyanka Kumari, Singh Surjit, Gill Kirandip
Abstract excerpt
Spanning three decades in research, Paraoxonases (PON1) carried potential of dealing with neurotoxicity of organophosphates entering the circulation and preventing cholinergic crisis. In the past few years, the Paraoxonase multigene family (PON1, PON2, PON3) has been shown to play an important role in pathogenesis of cardiovascular disorders including coronary artery disease (CAD). The PON genes are clustered in...
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