Article
Paraoxonase genes and disease.
Annals of medicine - 1 Jun 1999
Hegele R A
Abstract excerpt
The paraoxonase gene family contains at least three members, including PON1, PON2 and PON3, which are located on chromosome 7q21.3-22.1. Until recently, there has been little insight into the role of the respective gene products in human physiology and pathology. However, emerging evidence from biochemical and genetic experiments is providing clues about the role(s) of the products of these genes. For example,...
Topics
- Animals
- Arteriosclerosis
- Aryldialkylphosphatase
- Birth Weight
- Coronary Disease
- Diabetes Mellitus, Type 2
- Esterases
- Genetic Variation
- Humans
- In Vitro Techniques
- Lipoproteins, HDL
- Lipoproteins, LDL
- Mice
