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Article

The calcium channel subunit α2δ-3 organizes synapses via an activity-dependent and autocrine BMP signaling pathway.

Nature communications - 6 Dec 2019

Hoover Kendall M, Gratz Scott J, Qi Nova, Herrmann Kelsey A, Liu Yizhou, Perry-Richardson Jahci J, Vanderzalm Pamela J, O'Connor-Giles Kate M, Broihier Heather T

Abstract excerpt

Synapses are highly specialized for neurotransmitter signaling, yet activity-dependent growth factor release also plays critical roles at synapses. While efficient neurotransmitter signaling relies on precise apposition of release sites and neurotransmitter receptors, molecular mechanisms enabling high-fidelity growth factor signaling within the synaptic microenvironment remain obscure. Here we show that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31811118
DOI: 10.1038/s41467-019-13165-7
PMCID: PMC6898181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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