Article
Presence of copy number aberration and clinical prognostic factors in patients with acute myeloid leukemia: an analysis of effect modification.
Polish archives of internal medicine - 23 Dec 2019
Bănescu Claudia, Tripon Florin, Trifa Adrian P, Crauciuc Andrei G, Bogliș Alina, Lazar Erzsebet, Dima Delia, Macarie Ioan, Duicu Carmen, Iancu Mihaela
Abstract excerpt
INTRODUCTION: Acute myeloid leukemia (AML) is characterized by multiple acquired genetic events, chromosomal abnormalities such as copy number aberrations (CNAs), disease progression, and low survival rates. OBJECTIVES: We assessed the utility of a multiplex ligation-dependent probe amplification (MLPA) assay in AML as well as correlations of CNAs with various biological and clinical features of patients with...
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