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Article

Gene mutational pattern and expression level in 560 acute myeloid leukemia patients and their clinical relevance.

Journal of translational medicine - 22 Aug 2017

Zhu Yong-Mei, Wang Pan-Pan, Huang Jin-Yan, Chen Yun-Shuo, Chen Bing, Dai Yu-Jun, Yan Han, Hu Yi, Cheng Wen-Yan, Ma Ting-Ting, Chen Sai-Juan, Shen Yang

Abstract excerpt

BACKGROUND: Cytogenetic aberrations and gene mutations have long been regarded as independent prognostic markers in AML, both of which can lead to misexpression of some key genes related to hematopoiesis. It is believed that the expression level of the key genes is associated with the treatment outcome of AML. METHODS: In this study, we analyzed the clinical features and molecular aberrations of 560 newly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 28830460
DOI: 10.1186/s12967-017-1279-4
PMCID: PMC5568401

Genes

MEIS1
BAALC
FLT3
MECOM
WT1
DNMT3A
GATA2
KIT
NPM1
NRAS
ERG
IDH1
SPI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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