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Article

The pathogenesis of systemic lupus erythematosus: Harnessing big data to understand the molecular basis of lupus.

Journal of autoimmunity - 1 Jun 2020

Catalina Michelle D, Owen Katherine A, Labonte Adam C, Grammer Amrie C, Lipsky Peter E

Abstract excerpt

Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease that causes damage to multiple organ systems. Despite decades of research and available murine models that capture some aspects of the human disease, new treatments for SLE lag behind other autoimmune diseases such as Rheumatoid Arthritis and Crohn's disease. Big data genomic assays have transformed our understanding of SLE by providing...

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Identifiers

PMID: 31806421
DOI: 10.1016/j.jaut.2019.102359

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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