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Article

Precision medicine in systemic lupus erythematosus.

Nature reviews. Rheumatology - 1 Jun 2023

Fasano Serena, Milone Alessandra, Nicoletti Giovanni Francesco, Isenberg David A, Ciccia Francesco

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease that has diverse clinical manifestations, ranging from restricted cutaneous involvement to life-threatening systemic organ involvement. The heterogeneity of pathomechanisms that lead to SLE contributes to between-patient variation in clinical phenotype and treatment response. Ongoing efforts to dissect cellular and molecular heterogeneity in SLE could...

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Identifiers

PMID: 37041269
DOI: 10.1038/s41584-023-00948-y

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