Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The myopia susceptibility locus vasoactive intestinal peptide receptor 2 (VIPR2) contains variants with opposite effects.

Scientific reports - 3 Dec 2019

Leung Kim Hung, Luo Shumeng, Kwarteng Regina, Chen Sin-Guang, Yap Maurice K H, Huang Chien-Ling, Yip Shea Ping

Abstract excerpt

Myopia is the commonest eye disorder in the world. High myopes are predisposed to ocular pathologies. The vasoactive intestinal peptide receptor 2 (VIPR2) gene was identified as a myopia susceptibility locus by our group and another group. We continued to fine-map this locus. A case-control study was performed in 4 sequential stages with a total of 941 highly myopic subjects and 846 control subjects, all...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cohort Studies

Share to Haplotypes

Share to Linkage Disequilibrium

Share to Myopia, Degenerative

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 31796800
DOI: 10.1038/s41598-019-54619-8
PMCID: PMC6890636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The myopia susceptibility locus vasoactive intestinal peptide receptor 2 (VIPR2) contains variants with opposite effects.PMID 31796800Read ↗

Genetic susceptibility to refractive error: association of vasoactive intestinal peptide receptor 2 (VIPR2) with high myopia in Chinese.Semantic proximity Read ↗

A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population.Semantic proximity Read ↗

A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1.Semantic proximity Read ↗

Association of VIPR2 and ZMAT4 with high myopia.Semantic proximity Read ↗

Dysfunction of VIPR2 leads to myopia in humans and mice.Semantic proximity Read ↗

Myopia Genetics-The Asia-Pacific Perspective.Semantic proximity Read ↗

Fine mapping linkage analysis identifies a novel susceptibility locus for myopia on chromosome 2q37 adjacent to but not overlapping MYP12.Semantic proximity Read ↗

Common variants in chromosome 4q25 are associated with myopia in Chinese adults.Semantic proximity Read ↗

Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort.Semantic proximity Read ↗

[Advances in genome-wide association study of myopia].Semantic proximity Read ↗

TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis.Semantic proximity Read ↗

Association of high myopia with crystallin beta A4 (CRYBA4) gene polymorphisms in the linkage-identified MYP6 locus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.