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Article

Genetic susceptibility to refractive error: association of vasoactive intestinal peptide receptor 2 (VIPR2) with high myopia in Chinese.

PloS one - 1 Jan 2013

Yiu Wai Chi, Yap Maurice K H, Fung Wai Yan, Ng Po Wah, Yip Shea Ping

Abstract excerpt

Myopia is the most common ocular disease worldwide. We investigated the association of high myopia with the common single nucleotide polymorphisms (SNPs) of five candidate genes - early growth response 1 (EGR1), v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS), jun oncogene (JUN), vasoactive intestinal peptide (VIP), and vasoactive intestinal peptide receptor 2 (VIPR2). We recruited 1200 unrelated...

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Source

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Identifiers

PMID: 23637909
DOI: 10.1371/journal.pone.0061805
PMCID: PMC3630195

Genes

VIPR2
FOS
EGR1
JUN
VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Genetic susceptibility to refractive error: association of vasoactive intestinal peptide receptor 2 (VIPR2) with high myopia in Chinese.PMID 23637909Read ↗

The myopia susceptibility locus vasoactive intestinal peptide receptor 2 (VIPR2) contains variants with opposite effects.Semantic proximity Read ↗

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Comprehensive replication of the relationship between myopia-related genes and refractive errors in a large Japanese cohort.Semantic proximity Read ↗

Genome-Wide Association Study in Asians Identifies Novel Loci for High Myopia and Highlights a Nervous System Role in Its Pathogenesis.Semantic proximity Read ↗

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