Article
A genome-wide meta-analysis identifies two novel loci associated with high myopia in the Han Chinese population.
Human molecular genetics - 1 Jun 2013
Shi Yi, Gong Bo, Chen Lijia, Zuo Xianbo, Liu Xiaoqi, Tam Pancy O S, Zhou Xiangtian, Zhao Peiquan, Lu Fang, Qu Jia, Sun Liangdan, Zhao Fuxin, Chen Haoyu, Zhang Yiping, Zhang Dingding, Lin Ying, Lin He, Ma Shi, Cheng Jing, Yang Jiyun, Huang Lulin, Zhang Mingzhi, Zhang Xuejun, Pang Chi Pui, Yang Zhenglin
Abstract excerpt
High myopia, highly prevalent in the Chinese population, is a leading cause of visual impairment worldwide. Genetic factors play a critical role in the development of this visual disorder. Genome-wide association studies in recent years have revealed several chromosomal regions that contribute to its progression. To identify additional genetic variants for high myopia susceptibility, we used a genome-wide...
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