Article
Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort.
Investigative ophthalmology & visual science - 25 Jan 2012
Hysi Pirro G, Simpson Claire L, Fok Yvonne K Y, Gerrelli Dianne, Webster Andrew R, Bhattacharya Shomi S, Hammond Christopher J, Sham Pak C, Rahi Jugnoo S
Abstract excerpt
PURPOSE: To identify heritable genetic factors altering susceptibility to refractive error in the general population. METHODS: This was a genetic association study of refractive error investigating genetic polymorphisms in regions previously reported through linkage. Two study panels were drawn from the British 1958 Birth Cohort, composed of 2211 persons 44 years of age at the time of visit. Two main outcomes...
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