Article
Fine mapping linkage analysis identifies a novel susceptibility locus for myopia on chromosome 2q37 adjacent to but not overlapping MYP12.
Molecular vision - 1 Jan 2009
Schäche Maria, Chen Christine Y, Pertile Kelly Kathleen, Richardson Andrea Jane, Dirani Mohamed, Mitchell Paul, Baird Paul Nigel
Abstract excerpt
PURPOSE: Myopia (shortsightedness) is one of the most common ocular conditions worldwide and results in blurred distance vision. It is a complex trait influenced by both genetic and environmental factors. We have previously reported linkage of myopia to a 13.01 cM region of chromosome 2q37 in three large multigenerational Australian families that initially overlapped with the known myopia locus, MYP12. The...
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