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TMEM132D and VIPR2 Polymorphisms as Genetic Risk Loci for Retinal Detachment: A Genome-Wide Association Study and Polygenic Risk Score Analysis.

Investigative ophthalmology & visual science - 1 Sept 2023

Chuang Hao-Kai, Hsieh Ai-Ru, Ang Tien-Yap, Chen Szu-Wen, Yang Yi-Ping, Huang Hung-Juei, Chiou Shih-Hwa, Lin Tai-Chi, Chen Shih-Jen, Hsu Chih-Chien, Hwang De-Kuang

Abstract excerpt

Purpose: Retinal detachment (RD) is a sight-threatening ocular disease caused by separation of the neurosensory retina from the underlying retinal pigment epithelium layer. Its genetic basis is unclear because of a limited amount of data. In this study, we aimed to identify genetic risk loci associated with RD in participants without diabetes mellitus and to construct a polygenic risk score (PRS) to predict the...

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Identifiers

PMID: 37695605
DOI: 10.1167/iovs.64.12.17
PMCID: PMC10501492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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