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Article

Clonal relationship of synchronous head and neck cancer and esophageal cancer assessed by single nucleotide polymorphism-based loss of heterozygosity analysis.

BMC cancer - 3 Dec 2019

Sunpaweravong Somkiat, Bunbanjerdsuk Sacarin, Pongrujikorn Tanjitti, Naktang Chaiwat, Sunpaweravong Patrapim, Nitiruangjaras Anupong, Dechaphankul Tanadech, Jinawath Natini

Abstract excerpt

BACKGROUND: The prognoses of head and neck squamous cell carcinoma (HNSCC) and esophageal squamous cell carcinoma (ESCC) are poor, especially when both tumors occur at the same time. We examined the clonal relatedness of HNSCCs with synchronous ESCCs to confirm whether the second tumors were metastasis or separate second primary malignancies (SPMs) using loss of heterozygosity (LOH) analysis. METHODS: Twenty-one...

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Identifiers

PMID: 31795956
DOI: 10.1186/s12885-019-6394-6
PMCID: PMC6889604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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