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Article

The Radiogenomics of Late-onset Alzheimer Disease.

Topics in magnetic resonance imaging : TMRI - 1 Dec 2019

Bonham Luke W, Sirkis Daniel W, Hess Christopher P, Sugrue Leo P, Yokoyama Jennifer S

Abstract excerpt

Radiogenomics, defined as the integrated analysis of radiologic imaging and genetic data, is a well-established tool shown to augment neuroimaging in the clinical diagnosis, prognostication, and scientific study of late-onset Alzheimer disease (LOAD). Early work using candidate single nucleotide polymorphisms (SNPs) identified genetic variation in APOE, BIN1, CLU, and CR1 as key modifiers of brain structure and...

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PMID: 31794505
DOI: 10.1097/RMR.0000000000000222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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