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Article

Genetics of cognitive trajectory in Brazilians: 15 years of follow-up from the Bambuí-Epigen Cohort Study of Aging.

Scientific reports - 2 Dec 2019

Gouveia Mateus H, Cesar Cibele C, Santolalla Meddly L, Anna Hanaisa P Sant, Scliar Marilia O, Leal Thiago P, Araújo Nathalia M, Soares-Souza Giordano B, Magalhães Wagner C S, Mata Ignacio F, Ferri Cleusa P, Castro-Costa Erico, Mbulaiteye Sam M, Tishkoff Sarah A, Shriner Daniel, Rotimi Charles N, Tarazona-Santos Eduardo, Lima-Costa Maria Fernanda

Abstract excerpt

Age-related cognitive decline (ACD) is the gradual process of decreasing of cognitive function over age. Most genetic risk factors for ACD have been identified in European populations and there are no reports in admixed Latin American individuals. We performed admixture mapping, genome-wide association analysis (GWAS), and fine-mapping to examine genetic factors associated with 15-year cognitive trajectory in...

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Identifiers

PMID: 31792241
DOI: 10.1038/s41598-019-53988-4
PMCID: PMC6889148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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