Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Sept 2024

Xia Rui, Jian Xueqiu, Rodrigue Amanda L, Bressler Jan, Boerwinkle Eric, Cui Biqi, Daviglus Martha L, DeCarli Charles, Gallo Linda C, Glahn David C, Knowles Emma E M, Moon Jee-Young, Mosley Thomas H, Satizabal Claudia L, Sofer Tamar, Tarraf Wassim, Testai Fernando, Blangero John, Seshadri Sudha, González Hector M, Fornage Myriam

Abstract excerpt

INTRODUCTION: We conducted admixture mapping and fine-mapping analyses to identify ancestry-of-origin loci influencing cognitive abilities. METHODS: We estimated the association of local ancestry intervals across the genome with five neurocognitive measures in 7140 diverse Hispanic and Latino adults (mean age 55 years). We prioritized genetic variants in associated loci and tested them for replication in four...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition

Share to KIT gene

Share to Genome-Wide Association Study

Share to Hispanic or Latino

Share to Neuropsychological Tests

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 38946675
DOI: 10.1002/alz.14082
PMCID: PMC11497725

Genes

KIT
MTMR6
SLC24A2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Admixture mapping of cognitive function in diverse Hispanic and Latino adults: Results from the Hispanic Community Health Study/Study of Latinos.PMID 38946675Read ↗

Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics.Semantic proximity Read ↗

Identifying Individuals at High Risk for Alzheimer’s Disease Among Hispanics Using Single and Multi-Ancestry Polygenic Risk ScoresSemantic proximity Read ↗

Multi-ancestry meta-analysis and fine-mapping in Alzheimer’s DiseaseSemantic proximity Read ↗

Admixture Mapping of Alzheimer's disease in Caribbean Hispanics identifies a new locus on 22q13.1.Semantic proximity Read ↗

Cross-ancestry genome-wide association studies of brain imaging phenotypes.Semantic proximity Read ↗

APOE alleles' association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos-investigation of neurocognitive aging (HCHS/SOL).Semantic proximity Read ↗

Multi-ancestry studies in multi-omics of Alzheimer's disease: Recent insights and future directions.Semantic proximity Read ↗

Polygenic Risk Scores for Alzheimer’s Disease and Mild Cognitive Impairment in Hispanics/Latinos in the U.S: The Study of Latinos – Investigation of Neurocognitive AgingSemantic proximity Read ↗

Ancestry-specific effects of <i>APOE</i> on Alzheimer Disease EndophenotypesSemantic proximity Read ↗

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease.Semantic proximity Read ↗

Genetic Contributions to Alzheimer’s Disease and Frontotemporal Dementia in Admixed Latin American PopulationsSemantic proximity Read ↗

Genetic modifiers of APOE-ε4-associated cognitive decline.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.