Article

Epigenome-wide association study of level and change in cognitive abilities from midlife through late-life

2021-03-10

Abstract excerpt

<title>Abstract</title> <p>Background: Epigenetic mechanisms are important in aging and may be involved in late-life changes in cognitive abilities. We conducted an epigenome-wide association study of leukocyte DNA methylation in relation to level and change in cognitive abilities, from midlife through late-life in 535 Swedish twins. <h4>Results:</h4> Methylation levels were measured with the Infinium Human Methy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 35e77643-a643-5796-8c2b-18d7956f039a
DOI: 10.21203/rs.3.rs-167499/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Epigenome-wide association study of level and change in cognitive abilities from midlife through late-lifeDOI 10.21203/rs.3.rs-167499/v1Read

Pilot Study of Second-Generation DNA Methylation Epigenetic Markers in Relation to Cognitive and Neuropsychiatric Symptoms in Older AdultsSemantic proximity Read

Peripheral DNA Methylation, Cognitive Decline and Brain Aging: Pilot Findings from The Whitehall II Imaging StudySemantic proximity Read

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic TwinsSemantic proximity Read

Complex variation in measures of general intelligence and cognitive change.Semantic proximity Read

An epigenome-wide association study of sex-specific chronological ageingSemantic proximity Read

Blood-based epigenome-wide analyses of cognitive abilitiesSemantic proximity Read

Whole genome methylation sequencing in blood from persons with mild cognitive impairment and dementia due to Alzheimer’s disease identifies cognitive statusSemantic proximity Read

Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson’s DiseaseSemantic proximity Read

Exome-wide analysis reveals role of <i>LRP1</i> and additional novel loci in cognitionSemantic proximity Read

Neurostructural and cognitive signatures of novel polygenic risk scores for molecular brain agingSemantic proximity Read

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Semantic proximity Read

Epigenetic g predicts cognitive aging and incident dementia in a diverse, nationally representative sample of older adultsSemantic proximity Read