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An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality

2024-08-22

Abstract excerpt

<h4>ABSTRACT</h4> To understand how aging affects functional decline and increases disease risk, it is necessary to develop accurate and reliable measures of how fast a person is aging. Epigenetic clocks measure aging but require DNA methylation data, which many studies lack. Using data from the Dunedin Study, we introduce an accurate and reliable measure for the rate of longitudinal aging derived from cross-sect...

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Literature Corpus work
8b441408-9dc3-5404-a9da-ae896ffa269e
DOI
10.1101/2024.08.19.608305
Open publication

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An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortalityDOI 10.1101/2024.08.19.608305
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