Article
Prenatal exposure to organophosphate pesticides, maternal paraoxonase 1 genotype, and childhood neurodevelopment at 24 months of age in Shandong, China.
Environmental science and pollution research international - 1 Jan 2020
Wang Yiwen, Zhang Yan, Ji Lin, Zhou Yijun, Shi Rong, Kamijima Michihiro, Ueyama Jun, Gao Yu, Tian Ying
Abstract excerpt
Prenatal organophosphate pesticide (OP) exposure was reported to negatively affect childhood neurodevelopment. Paraoxonase 1 (PON1) is a key enzyme in the metabolism of OPs and may affect an individual's susceptibility to OP exposure. However, little is known about its role in the associations of prenatal OP exposure and childhood neurodevelopment. We measured dimethylphosphate (DM), diethylphosphate (DE), and...
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