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Article

Prenatal exposure to organophosphates, paraoxonase 1, and cognitive development in childhood.

Environmental health perspectives - 1 Aug 2011

Engel Stephanie M, Wetmur James, Chen Jia, Zhu Chenbo, Barr Dana Boyd, Canfield Richard L, Wolff Mary S

Abstract excerpt

BACKGROUND: Prenatal exposure to organophosphate pesticides has been shown to negatively affect child neurobehavioral development. Paraoxonase 1 (PON1) is a key enzyme in the metabolism of organophosphates. OBJECTIVE: We examined the relationship between biomarkers of organophosphate exposure, PON1, and cognitive development at ages 12 and 24 months and 6-9 years. METHODS: The Mount Sinai Children's Environmental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21507778
DOI: 10.1289/ehp.1003183
PMCID: PMC3237356

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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