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Article

Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.

Gynecologic oncology - 1 Jan 2020

Stasenko Marina, Tunnage Irina, Ashley Charles W, Rubinstein Maria M, Latham Alicia J, Da Cruz Paula Arnaud, Mueller Jennifer J, Leitao Mario M, Friedman Claire F, Makker Vicky, Soslow Robert A, DeLair Deborah F, Hyman David M, Zamarin Dimitriy, Alektiar Kaled M, Aghajanian Carol A, Abu-Rustum Nadeem R, Weigelt Britta, Cadoo Karen A

Abstract excerpt

OBJECTIVES: Assess outcomes of a clinical cohort of patients with endometrioid endometrial cancer (EEC) harboring somatic POLE exonuclease domain mutations (EDMs). METHODS: Patients were consented to a protocol of tumor-normal massively parallel sequencing of 410-468 cancer related genes. EECs subjected to sequencing from 2014 to 2018 were reviewed. Tumors with somatic POLE EDMs were identified. EECs were...

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Share to Carcinoma, Endometrioid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Polymerase II

Share to Endometrial Neoplasms

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Source

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Identifiers

PMID: 31757464
DOI: 10.1016/j.ygyno.2019.10.028
PMCID: PMC6980651

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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