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Article

Genomics of Primary and Metastatic Cutaneous Melanoma: A Systematic Review and Meta-Analysis.

American journal of clinical dermatology - 1 Sept 2026

Hoang Manh Duc, Bui Thi Oanh, Dao Van Tu, Le Van Quang, Lebbé Céleste, Bousquet Guilhem

Abstract excerpt

BACKGROUND: Melanoma is an aggressive skin cancer with limited durable responses despite therapeutic advances. Comprehensive characterization of genomic alterations may improve understanding of disease progression and inform therapeutic strategies. OBJECTIVE: We aimed to characterize genomic alterations in cutaneous melanoma and compare mutation prevalences between primary and metastatic tumors to improve...

Read the complete abstract on PubMed

Topics

Humans
Melanoma
Skin Neoplasms
Mutation
DNA Copy Number Variations
Genomics
Cutaneous Malignant Melanoma

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 42133201
DOI: 10.1007/s40257-026-01031-4
PMCID: PMC13578081

Genes

BRAF
NRAS
TERT
CDKN2A
NF1
PTEN
TP53
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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