Article
Genetic Predisposition to Drug-Induced Liver Injury.
Clinics in liver disease - 1 Feb 2020
Stephens Camilla, Andrade Raúl J
Abstract excerpt
Identification of genetic predisposition to drug-induced liver injury (DILI) is of paramount importance. Early candidate gene studies have identified various polymorphisms in drug-metabolizing genes that infer increased DILI susceptibility. Few of these have been confirmed in more recent genome-wide association studies, which have identified several specific human leukocyte antigen (HLA) alleles. The low...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
