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Article

Human ectoenzyme-expressing ILC3: immunosuppressive innate cells that are depleted in graft-versus-host disease

21 Nov 2019

Abstract excerpt

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is often associated with chemotherapy- and radiotherapy-induced host tissue damage, leading to graft-versus-host disease (GVHD). Innate lymphoid cells (ILC) have an essential role in tissue homeostasis and tissue repair via their production of interleukin (IL)-22, which acts on intestinal stem cells. The tissue healing capacities of ILC via IL-22 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31751473
DOI: 10.1182/bloodadvances.2019000176

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