Article
Functional and phenotypic heterogeneity of group 3 innate lymphoid cells.
Immunology - 1 Mar 2017
Melo-Gonzalez Felipe, Hepworth Matthew R
Abstract excerpt
Group 3 innate lymphoid cells (ILC3), defined by expression of the transcription factor retinoid-related orphan receptor γt, play key roles in the regulation of inflammation and immunity in the gastrointestinal tract and associated lymphoid tissues. ILC3 consist largely of two major subsets, NCR+ ILC3 and LTi-like ILC3, but also demonstrate significant plasticity and heterogeneity. Recent advances have begun to...
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