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Article

Human intrahepatic ILC2 are IL-13positive amphiregulinpositive and their frequency correlates with model of end stage liver disease score.

PloS one - 1 Jan 2017

Jeffery Hannah C, McDowell Patrick, Lutz Philipp, Wawman Rebecca E, Roberts Sheree, Bagnall Chris, Birtwistle Jane, Adams David H, Oo Ye Htun

Abstract excerpt

INTRODUCTION: Innate lymphoid cells (ILC) have been implicated in the initiation of inflammation and fibrosis in mice. However, ILC have not been characterized in inflamed human liver tissue. METHODS: Human intrahepatic lymphocytes were isolated by mechanical digestion and phenotyped by flow cytometry. Conditioned medium from cultures of primary human biliary epithelial cells, stellate cells, fibroblasts and...

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Identifiers

PMID: 29261670
DOI: 10.1371/journal.pone.0188649
PMCID: PMC5736232

Genes

CCL20
CCR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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