Article

Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines

2022-08-25

Abstract excerpt

A wide therapeutic repertoire has become available to oncologists including radio- and chemotherapy, small molecules and monoclonal antibodies. However, drug efficacy can be limited by genetic changes that allow cancer cells to escape therapy. Here, we designed a webtool that facilitates the data analysis of the Genomics of Drug Sensitivity in Cancer (GDSC) database on 265 approved compounds in association with a...

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Literature Corpus work: c8b7c5f2-f53a-5f9e-ba11-dc429cddbd83
DOI: 10.1101/2022.08.22.504894

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