Article
Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells.
Nucleic acids research - 1 Jan 2013
Yang Wanjuan, Soares Jorge, Greninger Patricia, Edelman Elena J, Lightfoot Howard, Forbes Simon, Bindal Nidhi, Beare Dave, Smith James A, Thompson I Richard, Ramaswamy Sridhar, Futreal P Andrew, Haber Daniel A, Stratton Michael R, Benes Cyril, McDermott Ultan, Garnett Mathew J
Abstract excerpt
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public resource for information on drug sensitivity in cancer cells and molecular markers of drug response. Data are freely available without restriction. GDSC currently...
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