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Article

mTCTScan: a comprehensive platform for annotation and prioritization of mutations affecting drug sensitivity in cancers.

Nucleic acids research - 3 Jul 2017

Li Mulin Jun, Yao Hongcheng, Huang Dandan, Liu Huanhuan, Liu Zipeng, Xu Hang, Qin Yiming, Prinz Jeanette, Xia Weiyi, Wang Panwen, Yan Bin, Tran Nhan L, Kocher Jean-Pierre, Sham Pak C, Wang Junwen

Abstract excerpt

Cancer therapies have experienced rapid progress in recent years, with a number of novel small-molecule kinase inhibitors and monoclonal antibodies now being widely used to treat various types of human cancers. During cancer treatments, mutations can have important effects on drug sensitivity. However, the relationship between tumor genomic profiles and the effectiveness of cancer drugs remains elusive. We...

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Identifiers

PMID: 28482068
DOI: 10.1093/nar/gkx400
PMCID: PMC5793836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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