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Article

Autofluorescence of NADH is a new biomarker for sorting and characterizing cancer stem cells in human glioma

20 Nov 2019

Abstract excerpt

Abstract Background The existing cell surface markers used for sorting glioma stem cells (GSCs) have obvious limitations, such as vulnerability to the enzymatic digestion and time-consuming labeling procedure. Reduced nicotinamide adenine dinucleotide (NADH) as a cellular metabolite with property of autofluorescence has the potential to be used as a new biomarker for sorting GSCs. Methods A method for sorting...

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PMID: 31747975
DOI: 10.1186/s13287-019-1467-7

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