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Article

Metabolic mapping of glioblastoma stem cells reveals NADH fluxes associated with glioblastoma phenotype and survival.

Journal of biomedical optics - 1 Mar 2020

Schroeder Alexandra, Pointer Kelli, Clark Paul, Datta Rupsa, Kuo John, Eliceiri Kevin

Abstract excerpt

SIGNIFICANCE: Glioblastoma multiforme (GBM) is the most frequently diagnosed adult primary brain malignancy with poor patient prognosis. GBM can recur despite aggressive treatment due to therapeutically resistant glioblastoma stem cells (GSCs) that may exhibit metabolic plasticity. AIM: Intrinsic nicotinamide adenine dinucleotide (NADH) fluorescence can be acquired with fluorescence lifetime imaging microscopy...

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Identifiers

PMID: 32216192
DOI: 10.1117/1.JBO.25.3.036502
PMCID: PMC7093735

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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