Article
The ultrastructural difference between CD133-positive U251 glioma stem cells and normal U251 glioma cells.
Ultrastructural pathology - 1 Dec 2012
Yang Bo, Wang You, Yang Chunxu, Ouyang Wen, Zhou Fuxiang, Zhou Yunfeng, Xie Conghua
Abstract excerpt
Glioma stem cells (GSC) have higher tumorigenic potential and stronger chemoresistance and radioresistance than normal glioma cells. The mechanisms behind these phenomena have remained elusive. The authors have isolated CD133-positive U251 GSCs from U251 glioma cells and detected the expression of stem cell markers (CD133 and nestin) of U251 GSCs by immunofluorescence staining. Then the ultrastructures of U251...
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