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Article

Melanocortin 4 Receptor Gene Sequence Analyses in Diverse Populations.

Genetic testing and molecular biomarkers - 1 Dec 2019

Edwards Michael A, Tattoli Tiffany, Sureja Gagan, Sykes Aaron, Kaniper Scott, Gerhard Glenn S

Abstract excerpt

Background: Melanocortin 4 receptor (MC4R) is a G-protein-coupled receptor involved in appetite regulation. Mutations in the MC4R gene are the most common cause of monogenic obesity. More than 200 sequence variants in the MC4R gene have been associated with obesity, although the vast majority of these data have been obtained from populations of European ancestry. The prevalence and mutation profile of MC4R is...

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Identifiers

PMID: 31742438
DOI: 10.1089/gtmb.2019.0175
PMCID: PMC6922060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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