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Article

Progression from a stem cell-like state to early differentiation in the C. elegans germ line.

Proceedings of the National Academy of Sciences of the United States of America - 2 Feb 2010

Cinquin Olivier, Crittenden Sarah L, Morgan Dyan E, Kimble Judith

Abstract excerpt

Controls of stem cell maintenance and early differentiation are known in several systems. However, the progression from stem cell self-renewal to overt signs of early differentiation is a poorly understood but important problem in stem cell biology. The Caenorhabditis elegans germ line provides a genetically defined model for studying that progression. In this system, a single-celled mesenchymal niche, the distal...

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Identifiers

PMID: 20080700
DOI: 10.1073/pnas.0912704107
PMCID: PMC2836686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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