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<i>Caenorhabditis elegans</i> as a model for stem cell biology

13 Apr 2010

Abstract excerpt

We review the application of Caenorhabditis elegans as a model system to understand key aspects of stem cell biology. The only bona fide stem cells in C. elegans are those of the germline, which serves as a valuable paradigm for understanding how stem-cell niches influence maintenance and differentiation of stem cells and how somatic differentiation is repressed during germline development. Somatic cells that...

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PMID: 20419785
DOI: 10.1002/dvdy.22296

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