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Article

Beta-catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions.

The EMBO journal - 18 Jun 2008

Kanamori Takahiro, Inoue Takao, Sakamoto Taro, Gengyo-Ando Keiko, Tsujimoto Masafumi, Mitani Shohei, Sawa Hitoshi, Aoki Junken, Arai Hiroyuki

Abstract excerpt

Asymmetric division is an important property of stem cells. In Caenorhabditis elegans, the Wnt/beta-catenin asymmetry pathway determines the polarity of most asymmetric divisions. The Wnt signalling components such as beta-catenin localize asymmetrically to the cortex of mother cells to produce two distinct daughter cells. However, the molecular mechanism to polarize them remains to be elucidated. Here, we...

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Identifiers

PMID: 18497747
DOI: 10.1038/emboj.2008.102
PMCID: PMC2396877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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