Article
AIJ: joint test for simultaneous detection of imprinting and non-imprinting allelic expression imbalance.
Mathematical biosciences and engineering : MBE - 10 Oct 2019
Chen Dao-Peng, Zhang Fang Yuan, Lin Shi Li
Abstract excerpt
Epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence. Genomic imprinting is an epigenetically regulated process by which imprinted genes are expressed in a parent-of-origin-specific manner. It can be confounded with a phenomenon, allelic expression imbalance (AEI), which, in this paper, refers to asymmetric...
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